Theweakeredge

"On the basis of the evidence reviewed here, I think it is fair to conclude that the traditional psychometric literature on cognitive ability—popularly resurrected in The Bell Curve—vastly overstates the case for the role of IQ in the stratification process. On the other hand, to say that the case has been overstated—even that it has been overstated with great lapses of scholarship and with racist overtones—does not say that there is no place for cognitive ability in our understanding of the stratification process. Both as defense against excessive claims on both sides of the “IQ debate” and in pursuing the scientific enterprise, we ought to seek and produce new evidence of the role of cognitive abilities in social stratification" (pg. 57)

"Polθ reverse transcribes RNA and promotes RNA-templated DNA repair"

Supporters of IQ testing have been quick to point to correlations between IQ and job performance as evidence of test validity. A closer look at the data and results, however, suggests a rather murkier picture. Here we have acknowledged the methodological advances in meta-analyses from which such evidence has been drawn, while drawing attention to the problems surrounding them in this particular area. We conclude with a summary of the main points:

1. Much in developmental theory, and psychology in general, depends upon the validity of IQ tests.
   
2. In the absence of agreed construct validity this has weighed heavily on indirect validity using correlations with criterion outcomes among which job performance has a special status.
   
3. Hundreds of studies prior to the 1970s reported low and/or inconsistent correlations between IQ and job performance.
   
4. These correlations have been approximately doubled using corrections for supposed errors in primary results and combining them in meta-analyses. Such corrections have many strengths, theoretically, but are compromised in these cases by the often uncertain quality of the primary studies.
   
5. The corrections to sampling errors, measurement errors, and to range restriction have required making a number of assumptions that may not be valid and have created a number of persistently contentious issues.
   
6. The claim that the IQ-job performance correlation increases with job complexity is not born out in more recent studies.
   
7. A range of other—including noncognitive—factors could explain a correlation between IQ and job performance, and even constitute part or all of the enigmatic “general factor.”
   
8. There remains great uncertainty about the interpretation of IQ-job performance correlations and great caution needs to be exercised in using them as a basis for the validity of IQ tests and associated concepts.
   

As others have pointed out, statistical corrections are no magical compensation for weak data and that it is risky to reach conclusions about test validities from those currently available (Oswald & McCloy, 2003; Russell & Gilliland, 1995). The only solution is properly conducted primary studies, with larger representative samples, better measures, and so on. Until they are available, investigators should be extremely cautious about disseminating conclusions about IQ test validities, from correlations between IQ and job performance.

Our study unexpectedly reveals that Polθ reverse transcribes RNA and undergoes a significant structural transformation to accommodate a DNA/RNA template. The structural transformation of Polθ’s thumb subdomain is likely needed to maintain productive interactions on DNA/RNA, which adopts a significantly different conformation relative to DNA/DNA in the Polθ complex

Polymerase θ (Polθ) is a unique DNA polymerase-helicase fusion protein in higher eukaryotes whose A-family polymerase domain evolved from Pol I enzymes (Fig. 1A) (1, 2). However, contrary to most Pol I enzymes, Polθ is highly error-prone and promiscuous

Together, these structural studies reveal that Polθ has an extraordinary degree of structural plasticity that enables it to efficiently transcribe template ribonucleotides and accommodate a full RNA-DNA hybrid within its active site. Although future studies will be required to fully elucidate the physiological relevance of Polθ RT activity, our findings demonstrate that Polθ accommodates template ribonucleotides in an active configuration and promotes RNA-DNA repair, which may contribute to cellular tolerance of genome-embedded ribonucleotides.

Polθ is not expressed in most tissues but is highly expressed in many cancer cells, which corresponds to a poor clinical outcome (13, 14). Furthermore, Polθ confers resistance to genotoxic cancer therapies and promotes the survival of cells deficient in DNA damage response pathways (11, 13–16). Thus, Polθ represents a promising cancer drug target.

No innocent person would destroy evidence

This is what I'd call a strawman - can I please get some foundational or representative fourth wave feminist literature or views that shares this "double standard"?